Topical composition for follicular delivery of an

专利名称：Topical composition for follicular delivery of

an ornithine decarboxylase inhibitor

发明人：Joyce T. Chou,Prakash Parab申请号：US10219087申请日：20020813

公开号：US20030053973A1公开日：20030320

摘要：Polyethylene glycol ethers of alkyl alcohols having the general formulaCH(CH)CH(OCHCH)OH wherein x is 8 to 20 (of which ceteareth-20, steareth-20 andsteareth-100 are preferred), poloxamer 185, poloxamer 407, N,N-dimethyl dodecylamineN-oxide, and mixtures thereof, are employed to increase follicular delivery and/orfollicular residence time of certain water soluble ornithine decarboxylase inhibitors ofwhich 2(difluoromethyl)-2,5-diamino pentanoic acid and its pharmaceutically acceptablesalts, hydrates, optical enantiomers and racemic mixture are preferred.

申请人：CHOU JOYCE T.,PARAB PRAKASH

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