Crystalline forms of zoledronic acid

专利名称：Crystalline forms of zoledronic acid发明人：CASPAR VOGEL,ALEXANDRA

GLAUSCH,HANS-JOACHIM WEBER,MICHAELMUTZ,HOLGER PETERSEN,JURGENSIGG,OLIVIER LOHSE

申请号：AU2007324833申请日：20071126公开号：AU2007324833A1公开日：20080605

摘要：The invention relates to new crystalline forms of low water soluble salts ofzoledronic acid, the process for preparation of these crystalline forms, compositionscontaining these crystalline forms, and the use of these crystalline forms in diagnosticmethods or therapeutic treatment of warm-blooded animals, especially humans. Theinvention relates to the crystalline form of the free acid monohydrate of zoledronic acid,the process for preparation of the crystalline form of the free acid monohydrate ofzoledronic acid, compositions containing the crystalline form of the free acidmonohydrate of zoledronic acid, and the use of crystalline form of the free acidmonohydrate of zoledronic acid in diagnostic methods or therapeutic treatment ofwarm-blooded animals, especially humans.

申请人：NOVARTIS AG

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