专利名称:Oligonucleotides and methods for the
preparation of RNA libraries
发明人:Jian Gu,Kelli Bramlett,Christopher Burnett申请号:US13774648申请日:20130222公开号:US09970048B2公开日:20180515
专利附图:
摘要:Disclosed are compositions and methods for the preparation of RNA librariesfor sequencing, gene expression profiling, microarray and other uses and forsimplification of the library preparation process. The disclosure provides blocking
oligonucleotides which bind to byproduct nucleic acid molecules formed during theligation of adapters to nucleic acid segments prior to sequencing and inhibit or blockamplification of the byproduct nucleic acid molecules in subsequent amplificationreactions. Methods for library preparation using blocking oligonucleotides are alsoprovided.
申请人:LIFE TECHNOLOGIES CORPORATION
地址:Carlsbad CA US
国籍:US
更多信息请下载全文后查看
因篇幅问题不能全部显示,请点此查看更多更全内容