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Oligonucleotides and methods for the preparation o

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专利内容由知识产权出版社提供

专利名称:Oligonucleotides and methods for the

preparation of RNA libraries

发明人:Jian Gu,Kelli Bramlett,Christopher Burnett申请号:US13774648申请日:20130222公开号:US09970048B2公开日:20180515

专利附图:

摘要:Disclosed are compositions and methods for the preparation of RNA librariesfor sequencing, gene expression profiling, microarray and other uses and forsimplification of the library preparation process. The disclosure provides blocking

oligonucleotides which bind to byproduct nucleic acid molecules formed during theligation of adapters to nucleic acid segments prior to sequencing and inhibit or blockamplification of the byproduct nucleic acid molecules in subsequent amplificationreactions. Methods for library preparation using blocking oligonucleotides are alsoprovided.

申请人:LIFE TECHNOLOGIES CORPORATION

地址:Carlsbad CA US

国籍:US

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