Induced regulatory T cell and use thereof

专利名称：Induced regulatory T cell and use thereof发明人：Rho Hyun Seong,Sung Kyu Lee申请号：US14747442申请日：20150623公开号：US10030226B2公开日：20180724

摘要：The present invention relates to a transduced T cell precursor prepared byintroducing a gene construct comprising a polynucleotide encoding C/EBP

(CCAAT/enhancer binding protein) to a T cell precursor and overexpressing the C/EBPthereby, wherein the transduced T cell precursor is capable of differentiating into aregulatory T cell and an induced regulatory T cell differentiated therefrom. Thetransduced T cell precursor and the induced regulatory T cell may be useful for

preventing and treating autoimmune diseases, inflammatory diseases and graft rejectionscaused by the malfunction of immune response.

申请人：SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION

地址：Seoul KR

国籍：KR

代理机构：Vorys, Sater, Seymour & Pease LLP

代理人：Mih Suhn Koh

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